A new drug, called orforglipron, can help people with diabetes manage their A1C and weight, according to topline results from a phase 3 trial by Eli Lilly.

Medical conditions can limit which weight loss pills work safely for you. For example, you should avoid phentermine if you have severe anxiety or hyperthyroidism. Nadler emphasizes the importance of taking anti-obesity medication only under the supervision of a health care professional.