FpnA, an Aspergillus fumigatus homolog of the human iron transporter ferroportin showed no iron efflux function in A. fumigatus but instead is important for resistance to nickel, cobalt ...
The company also develops IL-17 oral peptide antagonist PN-88,1 an oral metabolic/obesity peptide program, and an oral hepcidin mimetic/ferroportin blocker that is in pre-clinical stage. Protagonist ...
The company also develops IL-17 oral peptide antagonist PN-88,1 an oral metabolic/obesity peptide program, and an oral hepcidin mimetic/ferroportin blocker that is in pre-clinical stage. Protagonist ...
Iron supply to the kidney is dependent on systemic iron availability, which is regulated by the hepcidin-ferroportin axis. Most of the filtered plasma iron is reabsorbed in proximal tubules, a process ...
2023 Hepcidin inducer sapablursen Ionis Currently in phase II clinical trials for PV patients Ganz et al., 2023 Ferroportin inhibitor Vamifeport Vifor Currently in phase II clinical trials for SCD ...
It disrupts mitochondrial membrane potential and reduces glutathione and GPX4 expression. Ferroportin-1, a ferroptosis inhibitor, countered these effects. PGPC triggers ferroptosis through the CD36 ...
Hereditary hemochromatosis is an inherited iron overload disorder caused by inappropriately low hepcidin secretion leading to increased duodenal absorption of dietary iron, most commonly in C282Y ...
After hours: March 10 at 7:55:37 p.m. EDT Loading Chart for PTGX ...
Department of Nuclear Medicine, Xinqiao Hospital, Army Medical University, Chongqing 400037, China School of Medical Imaging, North Sichuan Medical College, NanChong 637100, China Department of ...
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