In these cases, a type of open heart surgery called the Fontan procedure is done as the final part of a series of surgeries needed to ensure healthy circulation in the body. The congenital heart ...

Alexander Egbe, MBBS: Thank you. Sameh Said, MD: Thank you. Dr Lyle: Can you give us a brief overview of the Fontan operation? Dr Said: The Fontan operation was initially designed by Francis ...

The Fontan operation, which places the systemic and pulmonary circulations in series and is driven by a single ventricular chamber, is the treatment of choice for patients born with one ventricle.

1 We report four cases of hepatocellular carcinoma in patients with congenital heart disease with univentricular physiology that was palliated by means of the Fontan procedure (Table 1).

1 The Fontan principle has since become well established for the management of single-ventricle circulations; however, many questions remain about the selection criteria for the procedure ...

More information: Muhammad Bakr Ghbeis et al, Biventricular Repair of Univentricular Heart Lowers Risk of Liver Disease Compared With the Fontan Operation, JACC: Advances (2025). DOI: 10.1016/j ...

For the two-part UNIVERSE study, 12 children who underwent the Fontan procedure were enrolled in a single-arm analysis of the pharmacokinetics, pharmacodynamics and safety of rivaroxaban (Xarelto ...

It is well-known that patients who undergo Fontan surgery slowly develop liver fibrosis for years post-operatively. In the past decade, these incidences have been steadily increasing and this is ...

Researchers from The Children’s Hospital of Philadelphia have identified risk factors for early and late mortality in pediatric cardiac patients who underwent a Fontan operation for single ...

While the Fontan procedure has improved the short- and mid-term outcomes for patients born with single ventricle anatomy, long-term complications of Fontan circulation include heart failure.

The letter by Asrani et al. (May 2 issue) 1 reports cases of hepatocellular carcinoma in patients who have undergone Fontan palliation for univentricular hearts. Our practice includes yearly ...