Embedded within the host-derived lipid envelope of Ebola virus are glycoprotein spikes that bind to cells and mediate fusion between the viral envelope and the host cell membrane, enabling the ...

Instead of attaching to the glycoprotein spikes of a fully assembled virus, and preventing it from entering a cell, many antibodies bound to the free-floating glycoproteins.

The spike protein of coronaviruses is one such viral glycoprotein. Ebola viruses have one, the influenza virus has two, ... There are estimated to be roughly 26 spike trimers per virus.

Using vesicular stomatitis virus (VSV) pseudotyped with CCoV-HuPn-2018 spike proteins, TGEV spike proteins, or HCoV-229E spike proteins, the scientists assessed the ability of APN orthologs to ...

Structure of Pangolin-CoV spike protein. A EM density representation from the 2.9 Å map of Pangolin-CoV S viewed from down the three-fold axis (top panel) and in the orthogonal view (lower panel).

Two human neutralizing antibodies have been isolated that bind to the glycoprotein spike of the SARS-CoV-2 virus and thereby prevent the virus from entering host cells. Although the antibodies ...

The core was positioned closer to the lipid membrane at the “proximal pole”, and at the “distal pole”, the outer glycoprotein spikes and inner membrane leaflet were either perturbed or missing. In ...

The spike protein of coronaviruses is one such viral glycoprotein. Ebola viruses have one, the influenza virus has two, ... There are estimated to be roughly 26 spike trimers per virus.

A druggable pocket in the SARS-CoV-2 Spike protein that could be used to stop the virus from infecting human cells has been discovered by an international team of scientists led by the University ...

The spike protein of coronaviruses is one such viral glycoprotein. Ebola viruses have one, the influenza virus has two, and herpes simplex virus has five. The architecture of the spike. The spike ...