Evidence suggests that in Parkinson’s disease, a breakdown in lysosomal function allows lipids to build up within cells. Variants of the GBA1 gene, the strongest genetic risk factor for sporadic PD, ...

It is clearly important to re-establish transport from the ER to form a new Golgi, which suggests that the delivery of ER-derived material is necessary. However, the large pool of vesicles in the ...

This is an important study utilizing innovative CRISPR based approaches demonstrating the role of the KLF family of transcription factors in the post natal maturation of cortical projection neurons.

Attribution (BY): Credit must be given to the creator. Single extracellular vesicle (EV) research holds the potential to revolutionize our understanding of cellular communication and enable ...

Congratulations to Mikael Rydén, the first Swede to be awarded the Camillo Golgi Prize. In 2025, the prize will be awarded for the fortieth time and it is awarded to Mikael Rydén at the Department of ...

The School of Pharmacy, Fujian Medical University, Fuzhou 350122, Fujian, P. R. China Innovative Drug Research Institute, Fujian Medical University, Fuzhou 350122, Fujian, P. R. China Fujian Key ...

Here, we describe the isolation and structure determination of proteins in membrane vesicles derived directly from cells. Structures of the ion channel Slo1 from total cell membranes and from cell ...

This fundamental research conducted a molecular comparison between smooth muscle cells and adjacent fibroblast cells within lung blood vessels affected by pulmonary arterial hypertension. The study ...

Persistent Link: https://ieeexplore.ieee.org/servlet/opac?punumber=42 ...