Membrane trafficking uses membrane-bound vesicles as transport intermediaries. Cargo molecules are enclosed within or associate with the membrane of these vesicles.

Secretion involves the release of proteins and other macromolecules by a cell. In eukaryotic cells, proteins synthesised at the ER are transported to the Golgi, where they are packaged into ...

In addition, STX3 overexpression causes an accumulation of vesicles near the apical plasma membrane and blocking in vesicle fusion (Low et al., 1998). STX5, found to be important in adipocyte vacuole ...

Quantitative measurements of intra-Golgi transport kinetics of diverse secretory cargos challenge the classic cisternal progression model and support the stable compartment model of the Golgi.

A recent study involving researchers from the University of Basel reveals that slowing down the intracellular transport of ...

A recent study involving researchers from the University of Basel reveals that slowing down the intracellular transport of ...

"Taken together, our findings suggest that Oxr1 and Ncoa7 regulate V-ATPase at the Golgi apparatus and trans-Golgi network to maintain optimal luminal pH for enzymatic activity," says Yoshimura.

Extracellular vesicles have emerged as promising tools in regenerative medicine due to their inherent ability to facilitate intercellular communication and modulate cellular functions. These nanosized ...

Abstract How the intra-Golgi secretory transport works remains a mystery. The cisternal progression and the stable compartment models have been proposed and are under debate. Classic cisternal ...

This article was originally published with the title “The Golgi Apparatus” in Scientific American Magazine Vol. 220 No. 2 (February 1969), p. 100 doi:10.1038/scientificamerican0269-100 ...