Chelico's lab studies immune responses to HIV, particularly a family of proteins called APOBEC3 which cause mutations in the HIV virus. Her research and others' show that the virus uses a ...

Antibodies are best known for their ability to latch onto and neutralize bacteria, viruses and other pathogens. But these ...

Lipids are the fatty molecules that make up cellular membranes, creating a protective barrier that regulates what enters and ...

3) Protein binds to HIV fragment on helper T cell and CD3 receptor on killer T cell, activating the killer T cell and bringing the two cells close together. 4) Activated killer T cell destroys HIV ...

described a bispecific antibody-like protein that attacks those reservoirs by coaxing HIV out of hiding and targeting infected cells for destruction. “In order to kill the [infected] cell, the cell ...

But more importantly, it also reacts to proteins that are incorporated into ... You have just produced a naked-DNA HIV vaccine. Trials for a genetic vaccine that may protect against AIDS began ...

a new study published in Cell Reports on November 22 finds that a protein produced by HIV called Nef can cause long-lasting chronic inflammation in a mouse model of HIV—and that the inflammation may ...

When we know the structure of a protein, we can attempt to design small drug molecules to bind to it and block its function. The power of this approach has been shown in the battle against HIV and ...

The vaccines tested delivered a ‘mosaic’ of HIV proteins designed to produce responses against a range of HIV subtypes. However the Imbokodo trial in African women and the Mosaico trial gay men and ...

Wesley Sundquist, a biochemist at University of Utah, and Tomas Cihlar, a virologist at Gilead, a biopharmaceutical company, have labored for more than a dozen years to turn one antiviral treatment, ...

The chemical structure that carries genetic instructions for protein synthesis. Although DNA is the primary genetic material of cells, RNA is the genetic material for some viruses like HIV. A protein ...

June 17, 2020 — To defend the body, the immune system makes proteins known as antibodies that latch onto the perceived threat, be it HIV, the new coronavirus or, as is the case in autoimmune ...