In 7 cases in which liver tissue was obtained, histologic changes of fatty metamorphosis, bile-duct proliferation, hepatic-cell necrosis and the presence of hyaline degeneration ("alcoholic ...

Liver inflammation is central to the pathogenesis of acute liver failure (ALF) where infiltration of myeloid cells in areas of hepatic necrosis is contrasted by systemic immune cell depletion and ...

Objective Liver injury impacts hepatic inflammation in part via Toll-like receptor (TLR) signalling. Triggering receptor expressed on myeloid cells 2 (TREM-2) modulates TLR4-mediated inflammation in ...

Alcoholic steatohepatitis with neutrophilic acute hepatitis and associated hepatocellular necrosis. Mild microvesicular and macrovesicular steatosis are observed, and architectural disarray ...

AI decision support system non-homogenously influences clinical decisions in dynamic treatment regimen, as it depends on several factors including prior knowledge, preference, disease type ...

Hepatocellular necrosis, hepatitis, and cholestasis in particular should arouse a greater degree of suspicion, especially if no other cause has been found. Drug-related liver damage is typically ...

Several cases of Ciprofloxacin induced hepatoxicity have been reported. These were characterized by extensive hepatocellular necrosis, mixed inflammatory Infiltrate and abundant esinophils in the ...

Consistent with the predominant hepatocellular necrosis, APAP-induced MPT may be a crucial cellular event contributing to hepatocyte death and liver injury during APAP hepatotoxicity. As MPT and JNK ...

Chronic liver diseases (CLD) such as hepatitis B and C virus infection, alcoholic liver disease, and non-alcoholic steatohepatitis are associated with hepatocellular necrosis, continual inflammation, ...