Palisade Bio presented a poster titled "PALI-2108, a Colon-Specific PDE4B Inhibitor Prodrug, Reduces Ulcerative Colitis Symptoms in an Acute Colitis DSS Mouse Model” at the Crohn's & Colitis Congress ...

Although gut microbiota and lipid metabolites have been suggested to be closely associated with type 2 diabetes mellitus (T2DM), the interactions between gut microbiota, ...

Data presented at the 2025 Crohn's and Colitis Congress PALI-2108 demonstrated to effectively reduce colitis symptoms in DSS mouse model without CNS toxicity associated with systemic exposure Company ...

Ileum sections were collected and stained with periodic acid ... 3′) and 515F (5′-GTGCCAGCMGCCGCGGTAA-3′) primers in lung and ileal tissue samples from mice in the ICH and sham groups. A TruSeq DNA ...

In this study, we present an intestinal tissue specific MNP isolation protocol to liberate high yields of viable, immature and biologically active MNPs from human intestinal jejunum, ileum and colon .

Alveolar type 2 cells are the main cell type coexpressing ACE2 and TMPRSS2 in lung tissue. In addition, ACE2 and TMPRSS2 are also coexpressed in both upper epithelial and gland cells from oesophagus ...

People's bodies can be old or young for their chronological age, depending, in part, on the amount and types of stressors ...

As these clocks have become widely available, multiple companies have begun to offer services that estimate people's biological age by comparing customer tissue samples to established epigenetic ...

A new study found that the brain may contain higher levels of microplastics, equivalent to the amount found in a standard ...

Microplastics were detected in almost every seafood sample found off the coast of the western U.S. in a recent study. The ...