Protein disulfide isomerases (PDIs) are essential enzymes that facilitate the proper folding of proteins and maintain protein quality within the endoplasmic reticulum.

Teas are known for their powerful properties that can help fight off inflammation in the body. Learn about 6 powerful teas ...

One unusual but significant cause of fatigue is an underactive thyroid, or hypothyroidism ... Another overlooked condition is chronic inflammation due to autoimmune diseases.

Nov. 13, 2024 — A new study by medicine safety experts found the use of gabapentinoids -- medicines widely used to treat neuropathic pain -- increased the risk of hip fractures, especially in ...

Feb. 11, 2025 — Researchers have discovered a new mechanism that is used by a male sex hormone essential for muscle and bone function. The findings could lead to the development of new drugs ...

In vivo, a collagen-induced arthritis model was developed in DBA mice to evaluate EFC's effects on inflammation, disease progression, and bone damage. RNA sequencing was utilized to identify the ...

synovitis and cartilage damage in mouse OA. Conclusions Our findings demonstrate that monocytes recruited via CCL2/CCR2, rather than by CCL5/CCR5, propagate inflammation and tissue damage in OA.

Most are in the neck. Also, includes swollen lymph nodes in the armpit or groin It's larger than the same node on the other side of the body Normal nodes are usually less than ½ inch (12 mm) across.

If you are living with pain, adding herbs to your regimen may help ease your discomfort, especially when combined with regular exercise, diet, and relaxation techniques. Inflammation is the body's ...

Its appearance depends on the rash's trigger. The affected area may be discolored, inflamed, and have pus-filled blisters. In some cases, a rash is itchy and accompanied by other symptoms, such as a ...