Oncogenic YAP accelerates S-phase entry by shortening G1, leading to replication stress and sensitivity to CHK1 inhibition.

A compound best known for giving almonds and apricots their aroma may be the key to defeating hard-to-kill cancer cells. Japanese researchers found that benzaldehyde can stop the shape-shifting ...

During therapy, some cancer cells evolve to escape elimination. Newer anticancer drugs that can overcome this resistance are ...

Metformin use may enhance progression-free survival (PFS) in patients receiving first-line systemic therapy for patients with ...

During therapy, some cancer cells evolve to escape elimination. Newer anticancer drugs that can overcome this resistance are necessary. Now, researchers from Japan demonstrate that aromatic ...

A recent study published in Genes & Diseases reveals a novel role of XPR1 in promoting ovarian cancer growth by regulating ...

Targeted Oncology connects oncology professionals with updates on immunotherapy, biomarkers, cancer pathways, and targeted ...

Did you know that a small molecule called NAD+ plays a critical role in our aging process? A deficiency of this molecule may ...

A recent study published in Genes & Diseases has unveiled a novel mechanism by which the restriction of YWHAB-mediated YAP cytoplasmic retention ...