Cancer drugs that inhibit CDK7 rapidly shut down pathways responsible for cell proliferation within minutes. For organs to ...

Background Fibrolamellar carcinoma (FLC), a rare and fatal liver cancer lacking effective drug therapy, is driven by the DNAJ-PKAc fusion oncoprotein. However, the underlying mechanism of DNAJ-PKAc’s ...

which serve as a "stop growing" signal that the lab has shown to inhibit cell proliferation in the ear during embryonic development. In their experiments, the scientists demonstrated that the ...

Review highlights how vitamin D, particularly its active form calcitriol, modulates immune responses, inflammation, and tumor ...

Cell crowding causes high-grade breast cancer cells to become more invasive by activating a molecular switch that causes the cells to shrink and spread.

Dronedarone emerged as a potent inhibitor of ESCC cell proliferation. Through a series of in vitro experiments, including cytotoxicity assays, cell proliferation tests, and anchorage-independent ...

Chinese scientists have discovered the transport mechanism of lactate -- a critical metabolic fuel for cancer cells -- and screened out silybin, a natural compound that disrupts this pathway to ...

Lung cancer (LC) is a major global health issue, with high mortality rates and limited therapeutic options. It is primarily categorized into non-small cell lung cancer (NSCLC) and small cell lung ...

A recent publication in Genes & Diseases has delivered a compelling synthesis of the latest insights into the cellular ...

Coffee or caffeine can alter circulating levels of sex hormone binding globulin, estrogen, C-peptide, and adiponectin. Coffee ...