Researchers have identified type 5 collagen as a key factor in kidney fibrosis, revealing its potential as a biomarker to predict chronic kidney disease progression. A repurposed anti-cancer drug, ...

The study, published in Science Translational Medicine, highlights the role of type 5 collagen - a minor component of scar tissue - in kidney fibrosis, and shows how an experimental therapy could ...

The patients had a median fibrosis stage of 1, as determined by trichrome stain. A median stiffness of 8.2 kPa and a FIB-4 of 2.032 were both predictors of stage 2 fibrosis. Importantly ...