The kidney is a central organ of the ... that will give rise to distal segments of the nephron. BRN1 commits cells to becoming cells of the Henle's loop and distal tubules. Irx genes, possibly ...

Professor Kenji Osafune (Department of Cell Growth and Differentiation) and his team of researchers have devised an effective ...

Genetic studies performed in humans and mutant mice have implicated a number of critical genes, in utero environmental factors and molecular mechanisms that regulate nephron endowment and kidney size.

Apr. 9, 2025 — Researchers have identified type 5 collagen as a key factor in kidney fibrosis, revealing its potential as a biomarker to predict chronic kidney disease progression. A repurposed ...

The main symptom of kidney stones is pain in your back, abdomen, or side. Some other symptoms include cloudy urine, a burning sensation when you urinate, and nausea. Kidney stones are one of the ...

The early stages of kidney damage may cause few or no symptoms. However, as damage accumulates and prevents the kidneys from functioning correctly, people may begin to notice symptoms. These may ...

Diabetes-related kidney disease can worsen and lead to failure. You may experience many different symptoms, including lower back pain, fatigue, and nausea or vomiting. If you have kidney disease ...

Potassium is essential for kidney function. Too much or too little potassium can affect this function and lead to complications. Potassium plays a key role in a number of bodily processes ...

If you'd asked us a few years ago if we’d heard of Loop Earplugs, we wouldn’t have known what you meant. After all, a device which lets you control the loudness of your surroundings seems too ...

For example, if you are taking one of these medications in combination with an NSAID or with a certain type of "water pill" (diuretic) known as a loop diuretic, or if you are dehydrated, there is an ...

Chronic kidney disease (CKD) is an umbrella term used to describe a longstanding disease or condition that causes the progressive loss of kidney (renal) function. Symptoms vary, depending on the stage ...

and the analysis of the consequences of kidney-specific gene knockouts on the distal nephron function. The acquired knowledge in these areas has allowed us to make a picture of the complex coordinated ...