In patients with kidney fibrosis, there is an imbalance between M1 and M2 macrophages. In this situation, M2 macrophages, which normally suppress inflammation, proliferate excessively and secrete ...

In sepsis-induced AKI, Csf2, which is a cytokine secreted by injured TECs, promotes the transition of M1 macrophages to M2 macrophages. Interestingly, certain M2 macrophages that express CD206 and ...

In patients with kidney fibrosis, there is an imbalance between M1 and M2 macrophages. In this situation, M2 macrophages, which normally suppress inflammation, proliferate excessively and secrete ...

This study reveals that neutrophil extracellular traps (NETs) drive macrophage-derived chemokine production (CXCL9/10/11) to promote CD8+ T cell ...

James George, Ph.D. James George, Ph.D., professor in the Division of Cardiothoracic Surgery, is the latest winner of the Heersink School of Medicine’s Featured Discovery. This initiative celebrates ...

This study unveiled the role of Lrrk2 gene in regulating macrophage polarization and immune response. This finding provides significant insights into the role of Lrrk2 in M1 macrophage modulation ...