PYC Therapeutics advances VP-001 for retinitis pigmentosa, gaining FDA insights for its upcoming registrational trial.

Through the program, gene therapies are developed to treat patients with retinitis pigmentosa caused by pathogenic variants ...

Ocugen, Inc. (Ocugen or the Company) (NASDAQ: OCGN), a pioneering biotechnology leader in gene therapies for blindness diseases, today announced that the ...

By blocking PROX1—and so preventing the suppression of new retinal cells—the team sustained retinal regeneration in mice with retinitis pigmentosa, a disease that occurs when photoreceptors in ...

S. Sakami et al., Probing mechanisms of photoreceptor degeneration in a new mouse model of the common form of autosomal dominant retinitis pigmentosa due to P23H opsin mutations. J. Biol. Chem. 286, ...

OCU400 shows significant long-term improvements in visual function and mobility for retinitis pigmentosa patients, ... validating the gene-agnostic mechanism of action for OCU400.

Ocugen, Inc. Announces Positive 2-Year Data Across Multiple Mutations from Phase 1/2 Clinical Trial of OCU400 —A Novel Modifier Gene Therapy for Retinitis Pigmentosa Ocugen Mon, Jan 13, 2025, 6: ...

OCU400 is intended for the treatment of early to advanced retinitis pigmentosa (RP) in pediatric and adult populations. Currently, about 2 million patients globally ... validating the gene-agnostic ...

The OCU400 EAP is available for patients with early, intermediate to advanced RP with at least minimal retinal preservation who may benefit from the mechanism of action of OCU400 prior to approval ...

AGTC-501 is an X-linked retinitis pigmentosa GTPase regulator (retinitis pigmentosa 15 or retinitis pigmentosa 3 GTPase regulator [RPGR]) activator. This has positive implications for patients, which ...

Retinal degeneration in the disease retinitis pigmentosa is caused by a family of hereditary mutations that slowly lead to blindness over years or decades. A mouse model of one of these forms of ...

Steven Pittler, Ph.D. Retinal degeneration in the disease retinitis pigmentosa is caused by a family of hereditary mutations that slowly lead to blindness over years or decades. A mouse model of one ...