Researchers have uncovered the 3D structure of RBP3, a key protein in vision, revealing how it transports retinoids and fatty ...

Proteins are fundamental biomolecules that perform a broad range of vital functions within the human body. They serve as an essential structural and functional component of cells, tissues and organs ...

Scientists have for the first time looked deep into the protein structure that may determine our vision - and discovered that ...

Shihabeddin et al utilized single-cell RNA-Seq analysis of adult P23H zebrafish animals to identify transcription factors (e2fs, Prdm1a, Sp1) expressed selectively in neural progenitors and immature ...

Edema describes swelling associated with injury, inflammation, or fluid overload. It happens when fluid from the small blood vessels leaks into tissues. Edema can affect a small or large area or even ...

Scientists have for the first time looked deep into the protein structure that may determine our vision - and discovered that it is much more dynamic than previously thought.

the detailed structure and mechanisms of RBP3 had remained largely unexplored, presenting a significant gap in the understanding of eye diseases associated with vision loss. Among the conditions ...

its structure and precise mechanisms of action have remained unknown until now. The lack of this information has been a significant gap in research on eye diseases, especially those leading to ...

Methods Initial testing involved eight patients with central retinal disease (Stargardt disease, STGD) and eight with peripheral retinal disease (retinitis pigmentosa, RP), who were examined using ...

KIO-301 is being developed for the treatment of retinitis pigmentosa, choroideremia, and Stargardt disease. It is a molecular photoswitch that has the potential to restore vision in patients with ...