Mitochondria are cell organelles surrounded by a double membrane. In addition to numerous essential functions in the ...

Mitochondria are cell organelles surrounded by a double membrane. In addition to numerous essential functions in the metabolism of the cell, they also play a key role in the integration of signals ...

Cold weather triggers brown fat to burn energy, thanks to a newly discovered protein switch. This natural calorie-burning ...

Mitochondria are the body's "energy factories," and their proper function is essential for life. Inside mitochondria, a set ...

Study results advance understanding of how human cells evolved and could help point to new solutions for patients with rare genetic diseases.

Mitochondria are the body's "energy factories," and their proper function is essential for life. Inside mitochondria, a set ...

Elizabeth Jonas first got interested in mitochondria by chance. In 1995, she was a postdoctoral researcher at Yale, working ...

Researchers at Tohoku University have discovered that an oral drug called MA-5 can improve both heart and muscle problems in ...

Researchers at Tohoku University have discovered that an oral drug called MA-5 can improve both heart and muscle problems in ...

Reactions involving the transfer of a phosphoryl (−PO32–) group are fundamental to cellular metabolism. These reactions are catalyzed by enzymes, often large and complex, belonging to the ...

The pathophysiology of heart failure is complex, but mitochondrial dysfunction is an emerging therapeutic target to improve cardiac function. In this Consensus Statement, insights into the ...

Deletion of capn4 or upregulation of ATP5A1 increased ATP synthase activity, prevented mitochondrial reactive oxygen species generation, and reduced proinflammatory response and myocardial dysfunction ...