Researchers mapped Y chromosome loss across thousands of individual cells from human cancers, with disturbing results.

a | The loss of mosaicism hypothesis states that extreme skewing of X chromosome inactivation causes breakdown of self tolerance in the thymus. b | The reactivation hypothesis claims that ...

Many examples of chromosome mosaicism have recently been reported. 19–24 In these, mosaicism could be confirmed by chromosome analysis, not possible in the present case.

Scientists at the USC Leonard Davis School of Gerontology have discovered a key connection between high levels of iron in the ...

A deeper understanding of how DNA changes over generations helps scientists learn why people differ and how diseases develop.

Such embryos also have high rates of mosaic aneuploidy, meaning that only some early blastomeres have abnormal chromosome number—indicating that mitotic nondisjunction events are also common, at ...

The Y chromosome, which plays a critical role in male development, is losing genetic material and may disappear in about 11 million years. Separately, a major 2017 study revealed that sperm counts in ...

By the age of 70, about 40% of men have lost the Y chromosome in at least some of their white blood cells. This condition, ...

Mosaic Loss of Y (LOY): A Prevalent Phenomenon Long before the Y chromosome potentially vanishes from the human species, many men are already experiencing its loss within certain cells. Commencing ...