Elie Naddaf, M.D., a consultant in the Department of Neurology, took an unusual and exciting next step in his career — he ...

It's no coincidence that our bodies feel a little creakier as we age. The trillions of cells that make up our skeleton age too, and some change in ways that weaken the very structure of our bones.

It's no coincidence that our bodies feel a little creakier as we age. The trillions of cells that make up our skeleton age too, and some change in ways that weaken the very structure of our bones.

Figure 4: Intracellular signalling in MLC/mIgf-1 transgenic muscle. Figure 5: MLC/mIgf-1 expression attenuates age-related genetic changes preserves skeletal muscle phenotype and regeneration in ...

The Exceptional Longevity Translational Resources (ELITE) Portal brings together multi-omic datasets to accelerate research into healthy aging. Centenarians with exceptional longevity are ...

One theory involves the physical changes that happen in muscle and connective tissue with age. As we get older, our skeletal muscles contain more collagen, which can stiffen both muscle and connective ...

Ageing is often accompanied by cognitive decline but is also the biggest known risk factor for Alzheimer's disease, the most common form of dementia. Emerging evidence suggests that sedentary and ...

Conversely, reduction in satellite cell content and function is a significant contributor for skeletal muscle wasting in many conditions, including aging and degenerative muscle disorders ...

Genome‐wide association studies have revealed numerous loci associated with coronary artery disease (CAD). However, some potential causal/risk genes remain unidentified, and causal therapies are ...