Multiple fatalities after car drives into crowd at festival; Millions in the path of severe weather; NBC News Stay Tuned Poll: 45% approve of Trump's job performance; and more on tonight’s broadcast.

As President Trump approaches his 100th day in office, a majority of Americans disapprove of his handling of the economy, ...

A new poll from NBC News and Stay Tuned shows warning signs for President Trump as he nears 100 days in office. NBC News' ...

A new study published Sunday in the New England Journal of Medicine reveals just how effective immunotherapy is at battling ...

There are growing questions about the circumstances surrounding the Trump administration's deportations of families. ICE says ...

There's good news about the rare instrument a Maryland man plays, and the joy he brings to his community. NBC News’ Hallie Jackson has the story.

Tens of thousands of people went to the Basilica of Santa Maria Maggiore to pay respects to the tomb of Pope Francis. It comes as the process to select the next pope is set to begin in days. NBC News’ ...

Tens of millions of people across multiple states are facing the threat of severe weather to start the week. NBC News’ ...

After freezing $2.2 billion in funding, the Trump administration has also singled out Harvard in other key ways: It ...

Noem’s bag was stolen by a masked man last Sunday while she was having dinner with her family in Washington, D.C.

Francis chose his place of burial because it reflects his “humble, simple and essential” life, the archbishop who administers the basilica said. Even in death, the pomp-shunning pontiff’s moral voice ...

Democrats are increasingly saying that simply unwinding Trump’s policies isn’t enough. But there are still broad ...