A research team led by Kyoto University said Wednesday it has prevented kidney functions from declining in mice using human ...

Meanwhile, only about 2,000 patients can receive new kidneys annually due ... more than 100-fold proliferation of nephron progenitor cells derived from human iPS cells compared with conventional ...

These important genetic associations identified in human renal hypoplasia have ... in the MM leading to a 50% decrease in both kidney size and nephron number in adult mice (33).

Patterning of the nephron along the proximal–distal ... and the developmental defects found in human patients. Induction of the kidney occurs through reciprocal interactions between an ...

More information: Toshikazu Araoka et al, Human iPSC–derived nephron progenitor cells treat acute kidney injury and chronic kidney disease in mouse models, Science Translational Medicine (2025).

Using UniMat, the team successfully produced kidney organoids featuring nephron structures and blood vessels similar to those found in human kidneys from human-induced pluripotent stem cells ...

A genetically engineered pig kidney helped Towana Looney enjoy 130 days without the need for dialysis before the organ was ...

The kidneys may be small, but they do big work, filtering waste, balancing fluids, and helping control blood pressure. While many people focus on liver or heart health, the kidneys get ignored ...

Doctors removed the kidney on April 4. Looney expressed gratitude for the research opportunity. Pig organs offer a potential solution to the human organ shortage. Xenotransplantation faces ...

While this change appears modest, sustained over decades it may accelerate normal age-related nephron loss. Hypertension remains the second leading cause of kidney failure, highlighting this ...