Participants were categorized as oral anticoagulant (OAC) naive (≤ 6 weeks of prior OAC use; n = 2493) or OAC experienced (> 6 weeks of prior OAC use; n = 12,317). Participants were randomly ...

(New Concord, Oh.) - Tobie Teke has a hot bat this spring. The Muskingum senior outfielder from Aurora is hitting .407 this season with a home run, 20 RBI, 23 stolen bases and 27 runs scored in 86 at ...

IgA nephropathy (IgAN) is characterized by the deposition of IgA1-containing immune complexes in the glomerular mesangium. The pathogenesis follows a 4-hit cascade: ...

Nuclear receptors form a family of proteins capable of accommodating a wide variety of small molecules in their ligand binding domain, ranging from therapeutic compounds to endocrine-disrupting ...

Here’s how Canada’s Old Age Security pension works, who’s eligible for OAS, when you can start receiving OAS, and the OAS payment dates in 2025. The money that funds the OAS comes from the ...

(Westerville, Oh.) - Kori Cornett is making a name for herself. For the first time in her collegiate career, she has been named the Ohio Athletic Conference (OAC) Athlete of the Week for her ...

Proteins change their conformations as part of their biological functions, for example, when binding another molecule (ligand). Two pathways are conceivable: Either the ligand binds preferentially to ...

(48) However, there remain over 100 GPCRs that are considered orphans, meaning that their native ligand or mode of activation have not been determined and their function may not be fully understood.

Patients with spontaneous coronary artery dissection (SCAD) who are discharged on oral anticoagulation (OAC) or dual antiplatelet therapy (DAPT) that combines aspirin plus ticagrelor have a higher ...