A landmark review in Nature Reviews Genetics dissects the rare and common genetic variants that shape human height. The paper ...

Historical trends and future projections of the number of people with overweight and obesity suggest alarming parallel increases in serious and potentially fatal comorbidities, particularly type 2 ...

Osteoarthritis (OA) is one of the most prevalent conditions affecting tens of millions of U.S. adults, traditionally ...

Bacteria naturally present in the human intestine (known as the gut microbiota) can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti-cancer immunity by blocking ...

Research from the University of Minnesota College of Pharmacy, published in Nature Communications, laid the groundwork for the first hormone-free ... retinoid signaling pathway with YCT-529 ...

This is in part because lung cells can be driven to a profibrotic phenotype by multiple pathways that reinforce each other, so that targeting one pathway alone may not be effective to slow or stop ...

The brief references a study of genetic variants—differences in DNA sequences—related to sex-hormone pathways. These pathways influence how the body produces or responds to hormones like testosterone ...

Surprisingly, they say this is a trend with some truth behind it. 'Cortisol is a hormone produced by the adrenal glands. It is essential in helping our body respond to stress (physical ...

Abscisic acid (ABA), a key environmental response hormone, strongly inhibits seed ... relationship between nitrate signaling and ABA pathways mediated through key transcriptional regulators.

The drug represents a significant advance in obesity pharmacology by simultaneously targeting two critical hormone pathways in the body. It activates what is known as glucose-dependent ...