Dobrolecki LE, Lewis MT. Surgical Procedure for Implantation of Human Tumor Tissue into the Epithelium-Free Mammary Fat Pad of Immunocompromised Mice to Generate Patient-Derived Xenografts (PDX).

“The assumption is that what grows out in the PDX is reflective of the bulk of the tumor in the patient,” study author and cancer geneticist Todd Golub, of both the Broad Institute, at MIT, and ...

Participants expressed that they would sacrifice an unlimited number of mice for their child, yet only 63% endorsed a willingness to use up to 1,000 mice per patient. Willingness to use more mice ...

The primary focus Patient-Derived Xenograft (PDX) Core is to develop, and provide to the Baylor PDX community, computational and bioinformatics infrastructure to support large scale generation, ...