In a first step toward FDA approval of kidney xenotransplantation, a living human with end-stage kidney disease may receive a ...

In a leukemia xenograft experimental model, repeated dosing of the tLNPs produced near-complete tumor clearance, underscoring the potential of this in vivo approach for treating both cancer and ...

In addition, the efficacies of 7 and 10 against the same tumor xenograft were assessed at doses below their respective MTDs. In all experiments, administration began two weeks after tumor implantation ...

Accumulating experimental evidence indicates that overexpression of the oncogenic receptor tyrosine kinase, Axl, plays a key role in the tumorigenesis and metastasis of various types of cancer. The ...