Furthermore, the emerging idea that glial cells can act as multipotent progenitors seems to be true not only in the CNS, but also in the PNS, as SCPs, like radial glia, can give rise to unexpected ...

Shihabeddin et al utilized single-cell RNA-Seq analysis of adult P23H zebrafish animals to identify transcription factors (e2fs, Prdm1a, Sp1) expressed selectively in neural progenitors and immature ...

Benraiss and Goldman also demonstrated that the same agents could induce new medium spiny neuron formation ... cell replacement therapies. Research in Goldman’s lab has shown that glial cells ...

From the Department of Cardiology and Angiology I, University Heart Center Freiburg, Germany (D.W.) Faculty of Medicine, University of Freiburg, Germany (D.W.) K. Ley has received research funding for ...

The data suggest that radial glial (RG) cells are indeed blocked prior to abscission ... While we do not directly observe failed abscission, the impaired furrow formation in Figure 3 and 5A aligns ...

Cartilage and bone development: Three paths to skeleton formation Date: March 27, 2025 Source: University of Basel Summary: In vertebrates, the skeleton of different regions of the body arises ...

those cells may then need a secondary inflammatory process to drive tumor formation. Knowledge about what pushes tumors to develop could be used for comprehensive personalized risk assessment ...

These domains promote interactions with neuronal proteins such as fibronectin leucine-rich repeat transmembrane proteins, promoting adequate synapse formation ... substrates of meprin β. HEK 293T ...

A man who was fully paralyzed is now able to stand after receiving an injection of reprogrammed stem cells into his injured ... transforming into neurons and glial cells. We’ve also seen ...

In fact, mutations in condensin structure can result in severe chromosome segregation defects and lead to cell death, cancer formation, or rare developmental disorders called 'condensinopathies.' ...

A newly identified form of regulated cell death, known as cuproptosis, may be a critical mechanism linking copper imbalance to vascular damage. The research is published in the journal ...