The ensemble of skeletal muscles can be considered the largest metabolic and endocrine organ of the human body. The more than ...

Brendan Lee, M.D., Ph.D., is the director of the lab. We are interested in the consequences of gene mutations on skeletal development and homeostasis. We combine studies on mammalian tissue and organ ...

Impairment in the skeletal muscle's capacity to efficiently use or store glucose can disturb overall glucose homeostasis, potentially resulting in insulin resistance—a major risk factor for type ...