When stimulated by the autonomic nervous system to contract from the release of hormones or other chemical signals, smooth muscle cells shorten via the movement of actin and myosin myofilaments.

For example, endothelial cells could sense vasoactive factors and provide signals to the vascular smooth muscle cells ... top of the cell surface. This actin-myosin mesh features linker proteins ...

We differentiated induced pluripotent stem cells from risk, nonrisk donors at 9p21.3, and isogenic knockouts into vascular smooth muscle cells (VSMCs). We performed single-cell transcriptomic ...

Unlike a natural iris, which relies on involuntary smooth muscle – which humans can’t control voluntarily – Raman's artificial muscle is built from skeletal muscle cells genetically tweaked to flex ...

The actin cytoskeleton is composed of dynamic filament networks that build adaptable local architectures to sustain nearly all cellular activities in response to a myriad of stimuli. Although the ...

SARS-CoV-2 cross-reactivity was also identified with target proteins to both striated and smooth muscles including actin and alpha-myosin. Actin is a major component of muscle that contributes to the ...

The molecular motor myosin V transports cargo by stepping on actin filaments, executing a random diffusive search for actin binding sites at each step. A recent experiment suggests that the joint ...