The mitotic spindle, an apparatus that segregates chromosomes during cell division, may be more complex than the standard textbook picture suggests.

The mitotic spindle, an apparatus that segregates chromosomes during cell division, may be more complex than the standard textbook picture suggests, according to researchers at Harvard. A new ...

During cell division, the motor protein kinesin-5 hastens or retards microtubule sliding in the mitotic spindle, imparting forces that scale with the degree of microtubule overlap.

Mitotic spindles use an elegant bipolar architecture to segregate duplicated chromosomes with high fidelity. Bipolar spindles form from a monopolar initial condition; this is the most fundamental ...

To better understand the role of kinesin-8 proteins in mitosis, we have studied the effects of deletion of the fission-yeast kinesin-8 proteins Klp5 and Klp6 on chromosome movements and spindle length ...

Flip of mitotic spindle has disastrous consequences for epithelial cells Date: July 21, 2013 Source: Stowers Institute for Medical Research Summary: Investigators have used genetics and live cell ...

The mitotic spindle includes thousands of microtubules, rod-like structures with polarized tips, which biologists term “plus ends” and “minus ends.” Because microtubules exist in great numbers ...

As division began, the mitotic spindle (which faithfully distributes chromosomes into each daughter cell) invariably oriented itself parallel to the apical surface of the epithelium.

Mitotic spindle: chromosomes in blue, microtubles in green. Wikimedia Commons/Afunguy Chromosomes are allocated by the mitotic spindle, which is made up of many thin filaments called microtubules ...