The combination therapy also led to a significant reduction in LDL-C levels, with an additional 13mg per decilitre (dL) of blood decrease compared to statins alone, measured from the start of ...

WASHINGTON — Statin use was associated with up to a 90% risk reduction for new-onset primary sclerosing cholangitis among patients with inflammatory bowel disease, according to data presented at ...

At 12 weeks, AZD0780 30mg taken once-daily led to a 50.7% reduction in LDL-C. Similar efficacy was observed regardless of whether trial participants received moderate- or high- intensity statin ...

The 2012 CTT meta-analysis was acknowledged in the 2013 Cochrane Review, which noted statin therapy "demonstrated a consistent 20% relative risk reduction in major vascular events with statins ...

Combining statins with another drug, ezetimibe, ... "This showed a 49% reduction in all-cause mortality and a 39% reduction in major adverse cardiovascular events, ...

Lipophilic statins had stronger protective associations, lowering HCC risk by 36% (aSHR 0.64), compared with a 21% risk reduction observed with hydrophilic statins such as rosuvastatin and ...

“Statins will remain the mainstay of this therapy due to the immense body of data in support of statin treatment on cardiovascular outcome reduction as well as the effectiveness of cholesterol ...

In the case of exposure to low or medium level air pollutants of PM10 (>50μg/m3) and PM2.5 (>25μg/m3), the statin prescribed group showed similar risk reduction.

For overall CVD incidence, there was a risk reduction observed for initiating statin therapy for adults aged 75 to 84 years (5-year standardized risk reduction, 1.20% in the intention-to-treat ...