Our laboratory studies both stem cell-intrinsic and extrinsic mechanisms altering tissue renewal capacity, and how such mechanisms ultimately result in the functional decline we recognize as aging.

Scientists at the University of California, Riverside, have discovered how adult stem cells retain their regenerative power.

Our immune systems weaken as we get older, making fewer cells that fight infection and help us recover from illness and ...

As we age, blood stem cells, the essential source of new blood cells in the body, can accumulate genetic mutations.

and protected populations of T cells with short telomeres from early aging, the team found. There was also an increase in the number of stem-like memory T cells, which are able to perform either ...

Scientists and researchers around the globe are investigating a series of mysteries about what happens to our bones over time.

He explained that the skin is the largest organ and undergoes both chronological and extrinsic ... of skin aging such as ...

The Silberstein lab initially became interested in Sema4A while looking for extrinsic, so called “niche” factors ... functional identity of myeloid-biased hematopoietic stem cells. Nature Aging. DOI: ...

Andre Catic, M.D., Ph.D. joined the Stem Cells and Regenerative Medicine Center and the Huffington Center on Aging at Baylor College of Medicine in 2014 as a CPRIT Scholar in Cancer Research. His ...

As we age, our skin undergoes two distinct processes: intrinsic aging, which happens naturally over time due to genetic ...

However, as we age, capacity of stem cells declines, and the resulting drop in tissue repair manifests as the functional decline associated with aging. Our goal is to understand why stem cell activity ...