The initiative aims to improve infectious disease management. T Cell Diagnostics Pte. Ltd. (TCD) has licensed an intellectual ...

T cells are a type of white blood cell that is central to your immune defense. Four types that serve different functions include: CD4 and CD8 are two different types of glycoprotein found on the ...

Bioprocessing has always been a bit late in adopting the latest engineering techniques, e.g., computational fluid dynamics to bioreactor design.

Credit: Juan Gaertner via Shutterstock. Chimeric antigen receptor (CAR) T cell therapies have made remarkable strides in treating high-risk B-cell malignancies since the first CAR-T, Novartis’s ...

Reproducibility of cell-based assays is one of the key points when it comes to reliability of experimental data. Despite of choosing the appropriate assay type, there are many more factors to be ...

Citation: Successful CAR-T cell therapy for end-stage multiple myeloma using advanced cellular product performed in Hong Kong (2025, March 27) retrieved 24 April 2025 from https://medicalxpress ...

“You don't have the luxury of doing that anymore. If it's the first time your data comes out, that's it.” In shifting its strategy, Nkarta joined more than a dozen companies vying to reproduce that ...

Chimeric antigen receptor (CAR) T-cell therapy has transformed the treatment of refractory or relapsed leukemia and hematologic malignancies, particularly over the past decade. Despite its ...

If the peptides are foreign antigens, the T cells expand in numbers and transform into an activated state, specialized to eradicate the pathogen. If the dendritic cell is carrying a "self-peptide ...

Crosstalk between dendritic cells and T cells plays a crucial role in modulating immune responses in natural and pathological conditions. DC-T cell crosstalk is achieved through contact-dependent (i.e ...