Total internal reflection fluorescence (TIRF) microscopy, a technique that has found wide use in single molecule and vesicle trafficking studies at membrane surfaces, relies upon essentially the same ...

In recent years, Total Internal Reflection Fluorescence (TIRF) microscopy has become an important method for studying molecular interactions near the cell surface. To accommodate the trend of the ...

Major microscope manufacturers, including Zeiss, Nikon, and Olympus, offer "turnkey" TIRF systems costing upwards of $100,000. But you can also upgrade an existing microscope to this capability.

Hu is using TIRF, a type of microscopy that will allow him to track the individual molecules as they come together to form the kinetochore. He can tag different kinetochore components with a molecule ...