When blood levels of thyroid hormones fall, the hypothalamus (in your brain) releases a hormone (thyrotropin-releasing hormone) that communicates with the pituitary gland. In response, the ...

Thyrotropin-releasing hormone (TRH) is a small yet highly significant tripeptide consisting of the amino acids pyroglutamate, histidine, and proline. First identified in the hypothalamus ...

Conversely, the strategy of first-line TSH measurement can miss patients with CH. In this Review, we focus on prevalence of CH and thyroid hormone status, particularly serum TSH level in each ...

For more than twenty-five years, TSH methods have been able to detect the TSH elevations that are characteristic of primary hypothyroidism. Modern-day TSH methods however, with their enhanced ...