Thyrotropin-releasing hormone (TRH) is a small yet highly significant tripeptide consisting of the amino acids pyroglutamate, histidine, and proline. First identified in the hypothalamus ...

When blood levels of thyroid hormones fall, the hypothalamus (in your brain) releases a hormone (thyrotropin-releasing hormone) that communicates with the pituitary gland. In response, the ...

For more than twenty-five years, TSH methods have been able to detect the TSH elevations that are characteristic of primary hypothyroidism. Modern-day TSH methods however, with their enhanced ...

Historically, the "quality" of a serum TSH method has been determined from a clinical benchmark - the assay's ability to discriminate euthyroid levels (~ 0.4 to 4.0 mIU/L) from the profoundly low ...