Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio for cystic fibrosis, where Vertex therapies ... and small-molecule inhibitors of APOL1-mediated kidney diseases.

As it advances, excessive fibrosis or buildup of scar tissue impairs the ability of the kidneys to filter toxins from the blood and reabsorb water, often leading to kidney failure. There are ...

The study, published in Science Translational Medicine, highlights the role of type 5 collagen - a minor component of scar tissue - in kidney fibrosis, and shows how an experimental therapy could ...

The study, published in Science Translational Medicine, highlights the role of type 5 collagen — a minor component of scar tissue — in kidney fibrosis, and shows how an experimental therapy could help ...

The study, published in Science Translational Medicine, highlights the role of type 5 collagen — a minor component of scar tissue — in kidney fibrosis, and shows how an experimental therapy ...

reduced signs of kidney injury in these mice. Overexpression of PPDPF improved mitochondrial activity, increased NAD + levels, enhanced NMNAT activity, and reduced markers of fibrosis and injury ...

American Liver Foundation. Fibrosis (scarring). National Institute of Diabetes and Digestive and Kidney Diseases. Definition & facts of NAFLD & NASH. Osna NA, Donohue TM Jr, Kharbanda KK.

(WLS) -- Katie Pappas' doctors told her, not only does she need another kidney donation after having ... The 40-year-old Timber Trails Elementary School health teacher spends her days bringing ...

People living with cystic fibrosis can now take a once-daily drug that will help them breathe easier all day long, thanks to ...