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Nephron formation is continuous ... Irx genes, possibly together with BRN1, control the fate of the intermediate tubule cells, which will give rise to the Henle's loop in mammals.
The distal portions of the nephron, including the distal convoluted tubule (DCT), the connecting tubule (CNT), and the cortical collecting duct (CCD), are essential to fine-tune the excretion of ...
1006 + 1 G>A splice-site), encoding the renal sodium–inorganic PO4 cotransporter NaPi-IIa, which mediates sodium-dependent PO4 reabsorption in the proximal renal tubule cells. Surprisingly, within two ...
ClC-K2 is expressed more broadly in the distal nephron; expression levels are highest along the thick ascending limb of the loop of Henle and distal convoluted tubule. Expression of ClC-K1 is ...