This is a potentially valuable modeling study on sequence generation in the hippocampus in a variety of behavioral contexts. While the scope of the model is ambitious, its presentation is incomplete ...

CPGs. Their model shows that cell-type-specific connectivity and a dominant inhibitory drive could underlie rhythm generation. Excitatory input could act to enhance the frequency range of these ...

This study proposes a potentially useful improvement on a popular fMRI method for quantifying representational similarity in brain measurements by focusing on representational strength at the single ...

During the peer-review process the editor and reviewers write an eLife assessment that summarises the significance of the findings reported in the article (on a scale ranging from landmark to useful) ...

Department of Pharmacology and Molecular Sciences, Johns Hopkins University, Baltimore, United States ...

This study provides useful information on the impact of Lamin A/C knockdown on gene expression using RNA-Seq analysis. In addition, the impact of Lamin A/C knockdown on telomere dynamics is explored ...

This study presents compelling evidence that the denitrosylase SCoR2 regulates cardioprotective metabolic reprogramming in the heart following ischemia/reperfusion injury. The findings are supported ...

This study introduces a novel and broadly applicable metric-phenological lag-to partition the effects of spring warming from other abiotic constraints on plant phenology. While the dataset is ...

During the peer-review process the editor and reviewers write an eLife assessment that summarises the significance of the findings reported in the article (on a scale ranging from landmark to useful) ...

Projection-specific optogenetic and chemogenetic experiments reveal a hippocampal-lateral septal pathway that potentially acts via the ventral tegmental area to regulate social novelty preference ...

Abstract Maize originated from teosinte parviglumis following a subspeciation event occurred in volcanic regions of Mesoamerica. The elucidation of the phenotypic changes that gave rise to maize have ...

Researchers have used high-throughput neutralisation assays to reveal how gaps in individual immunity shape the success of circulating flu strains.