Objectives This 1-year long-term extension (LTE) study ( NCT04451772) followed the 48-week phase 2 SLEek study (NCT03978520) that evaluated upadacitinib (a Janus kinase inhibitor) alone or combined ...

Objective Synovial inflammation plays a crucial role in osteoarthritis (OA) by producing key cytokines that mediate synovium–cartilage interaction and drive damage progression. In this study, we aimed ...