Clinical Trials Arena1d
Persica’s antibiotic-based drug alleviates lower back pain in Phase Ib trial
Persica's antibiotic-based drug could benefit patients with chronic lower back pain who are suffering from an infection in ...
Clinical Trials Arena1d
Everest Medicines begins dosing in mRNA cancer vaccine trial
Everest Medicines has dosed the first subject with EVM16, the company’s personalised mRNA cancer vaccine, in the EVM16CX01 ...
clinicaltrialsarena1d
J&J drops Phase III MDD programme due to lack of efficacy
J&J is now looking to trial the therapy in other indications but has not specified details. Image credit: Shutterstock / josefkubes. Johnson & Johnson (J&J) is dropping its Phase III major depressive ...
clinicaltrialsarena1d
Merck KGaA’s lupus drug fails in SLE cohort of Phase II trial
Merck is continuing development of its lupus therapy despite the negative announcement. Image credit: ricochet64 / Shutterstock. Merck KGaA’s oral TLR7/8 inhibitor enpatoran has failed to meet the ...
clinicaltrialsarena2d
Neurocrine Biosciences initiates trial of VMAT2 inhibitor in healthy adults
NBI-1140675 is under development for treating certain neuropsychiatric and neurological conditions. Credit: SewCreamStudio/Shutterstock. Neurocrine Biosciences has ...
Clinical Trials Arena3d
FDA puts clinical hold on BioNTech’s malaria vaccine trial
The US FDA has ordered BioNTech to immediately halt its Phase I/II trial of BNT165e, a malaria vaccine candidate, pending ...
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Bloom Science’s obesity therapy sustains weight loss after final dosing
The safety and efficacy study recruited 32 healthy adults ranging in body weight from healthy weight to overweight. Credit: Shutterstock / leolintang. Bloom Science’s trial examining its primary ...
clinicaltrialsarena3d
PepGen pauses Phase II DMD trial to review safety data
PepGen’s stock, which is listed on the Nasdaq market, dropped by 18% after the company announced the news. Image credit: Andrii Yalanskyi / Shutterstock PepGen is pausing the initiation of a new Phase ...
Clinical Trials Arena4d
Biohaven’s pivotal bipolar drug trial fails, stock takes hit
Biohaven’s pipeline drug BHV-7000 has failed to meet the primary endpoint in a pivotal Phase II/III bipolar trial.
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Daiichi Sankyo and AstraZeneca’s Enhertu shows OS improvements in Phase III trial
DESTINY-Gastric04 claims to be the first Phase III trial to evaluate the ADC in HER2-positive advanced gastric cancer. Credit: SewCreamStudio / Shutterstock. Daiichi Sankyo and AstraZeneca’s Enhertu ...
clinicaltrialsarena4d
CStone doses first subject in trial of CS2009 for advanced solid tumours
The Phase I trial is currently underway in Australia, with plans to extend into the US and China. Credit: Volha_R/Shutterstock. CStone Pharmaceuticals has dosed the first subject in the multicentre ...
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Pliant Therapeutics stock tumbles amid IPF trial cancellation
The announcement comes after Pliant confirmed in February 2025 that it would pause the trial awaiting the monitoring board’s decision. Credit: Shutterstock / Lisa F Young Pliant Therapeutics has ...