The autophagy-lysosomal pathway is activated via ... including Taxol resistant A549 Taxol cells. This study revealed that Hdy-7 induces ROS-mediated lysosomal biogenesis and retards cell growth ...

In a historic two-day rout last week, the world’s 500 wealthiest individuals have collectively lost more than half a trillion dollars, marking the steepest loss ever recorded on the Bloomberg ...

This break may allow it to focus energy elsewhere, such as on repairing the body. The concept of autophagy is also popular with proponents of intermittent fasting. In the simplest terms ...

When you fast, the cells in your body start a cellular waste removal process called autophagy. In this process, the cells break down and metabolize broken and dysfunctional proteins that build up ...

Intermittent fasting may also support brain health through increased autophagy. Autophagy is your body’s way of replacing damaged cells with healthy ones. Research suggests that it may safeguard ...

These PARP14/ADPr condensates contain key components of p62 bodies—including the selective autophagy receptor p62, its binding partner NBR1 and the associated protein TAX1BP1, along with K48-linked ...

Sunitinib is an approved therapy for treatment of patients with PNETs, but low response rates and resistance have limited its impact, with autophagy and sunitinib sequestration in the lysosome ...

Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), Guangxi Key Laboratory of Chemistry and Molecular Engineering of Medicinal Resources, ...

Autophagy is a cellular degradation process that plays a crucial role in maintaining metabolic homeostasis under conditions of stress or nutrient deprivation. This process involves sequestering, ...

Mammalian target of rapamycin (mTOR) is pivotal for cell growth and metabolism. The downstream targets of mTOR regulate protein translation and cell autophagy to affect orthoflavivirus replication, ...