When you fast, the cells in your body start a cellular waste removal process called autophagy. In this process, the cells break down and metabolize broken and dysfunctional proteins that build up ...

Some supplements and drinks may break a fast. This can depend on whether they contain certain ingredients, including sugar. Fasting is becoming a popular lifestyle choice. Fasts don’t last ...

These PARP14/ADPr condensates contain key components of p62 bodies—including the selective autophagy receptor p62, its binding partner NBR1 and the associated protein TAX1BP1, along with K48-linked ...

In a historic two-day rout last week, the world’s 500 wealthiest individuals have collectively lost more than half a trillion dollars, marking the steepest loss ever recorded on the Bloomberg ...

The autophagy-lysosomal pathway is activated via ... including Taxol resistant A549 Taxol cells. This study revealed that Hdy-7 induces ROS-mediated lysosomal biogenesis and retards cell growth ...

School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, the University of Dublin, College Green, Dublin 2 D02 PN40, Ireland Trinity Translational Medicine Institute, Trinity College ...

Sunitinib is an approved therapy for treatment of patients with PNETs, but low response rates and resistance have limited its impact, with autophagy and sunitinib sequestration in the lysosome ...

I am Reader and Principal Investigator at the University of Surrey, United Kingdom. I obtained my PhD in Virology in the University of Barcelona. I then joined the laboratory of Claude Krummenacher ...

College of Korean Medicine, Kyung Hee University, Seoul 02447, Republic of Korea Department of Internal Medicine, Kyung Hee University Korean Medicine Hospital, Seoul 02447, Republic of Korea ...

U2OS, A549, and HEK293Ta cells were maintained in DMEM (Sigma) with Glutamax (Gibco), 6% fetal bovine serum (Biological Industries), and 1% Pen/Strep (Biological Industries). MDA-MB-231 cells were ...