Non-alcoholic fatty liver disease (NAFLD) is a hepatic metabolic syndrome resulting from lipid metabolic imbalance.

Non-alcoholic fatty liver disease (NAFLD) is a hepatic metabolic syndrome resulting from lipid metabolic imbalance.

This finding indicates that the IRF8/BMAL1/ PPARγ axis may play an important role in liver lipid metabolism. Furthermore, adeno-associated virus-mediated IRF8 knockdown in mouse liver markedly ...

Removing EPO signaling in mouse liver tumors leads to tumor regression along with sensitivity to immunotherapy.

Cold' tumors are resistant to common immunotherapies. Researchers have uncovered a master regulator that can be manipulated to prevent tumor growth in mice.

Blocking the activity of the protein turns formerly "cold," or immune-resistant, liver tumors in mice into "hot" tumors teeming with cancer-fighting immune cells. When combined with an ...

The researchers set out to fill the gap by comparing the livers of healthy and obese mice. Their measures showed a clear difference between the hub molecules of healthy and obese liver cells. The ...