Alzheimer's disease (AD) is a debilitating neurodegenerative condition that affects a significant proportion of older people ...

The speed of the action potential isn't constant, they assert, but modulated by changes in the size of the nano-pearls, which in turn are caused by mechanical changes in the axon's membrane and ...

That, in turn, modulates the speed of the action potential. So, axons are highly flexible in that sense.” Flash-freezing before imaging led to discovery ...

Myelin is the fatty membranes of cells called Oligodendroglia (in the CNS) and Schwann Cells (in the PNS) that wraps around the axon and acts as an insulator, preventing the dissipation of the ...

In this paper, the authors investigate compound action potentials formed when the underlying tract's axons have current-mediated coupling amongst themselves, and no field-mediated coupling. The key ...

Article citations More>> Chawla, A., Morgera, S. and Snider, A. (2019) On Axon Interaction and Its Role in Neurological Networks. IEEE/ACM Transactions on Computational Biology and Bioinformatics, 18, ...

Activity-dependent plasticity of the axon initial segment (AIS) endows neurons with the ability to adapt action potential output to changes in network activity. Action potential initiation at the AIS ...

Mammalian axons are specialized for transmitting action potentials to targets within the central and peripheral nervous system. A growing body of evidence suggests that, besides signal conduction, ...

Most often, it is potassium (K +) and sodium (Na +) ions that generate the action potential. Ions move in and out of the axons through voltage-gated ion channels and pumps.

In suggesting that axons can initiate action potential firing, the new findings challenge an established concept in neurobiology: that action potentials start in the cell body or “soma” of ...