However, it poorly transduces a number of human cells and tissues, mainly because they lack the Coxsackie adenovirus receptor (CAR). A new adenovirus vector has been developed where the fiber gene ...

Major new analysis from the Thrombotic Thrombocytopenia Syndrome (TTS) Consortium has provided critical insights into the ...

Circumvention of anti-adenovirus neutralizing immunity by administration of an adenoviral vector of an alternate serotype Hum Gene Ther 1997 8: 99–109 Article CAS PubMed Google Scholar ...

In May 2023, Johnson & Johnson's Janssen unit requested the voluntary withdrawal of its emergency use authorization for its adenoviral vector COVID vaccine in the U.S., saying the company did not ...

It is a non-replicating adenovirus vector-based therapy containing the gene interferon alfa-2b, administered locally as a monotherapy by catheter directly into the bladder once every three months.

Adstiladrin is a nonreplicating adenoviral vector-based gene therapy that delivers a copy of a gene encoding a human interferon-alfa 2b (IFNα2b) to the bladder urothelium.

With more than 30 years of experience working with adenoviral vectors, Mittal is a leader in designing human and nonhuman adenoviral vectors for recombinant vaccines. Over the last 20 years, he has ...

New conditionally replicative adenovirus vector with synNotch receptor gene for MIBC treatment March 25, 2025 The MIBC subtype accounts for around 25% of all BC cases, with a significant proportion of ...