The 8-year data may hold value for TAVI—the newest Sapien valve uses the same tissue—but many other variables differ.

"The decision between a bioprosthetic and a mechanical valve is one of the most consequential for patients requiring aortic ...

aHR 1.12 favoring bioprosthetic valves (95% CI 0.97-1.29) These findings were consistent in sensitivity analyses excluding pure aortic insufficiency, intermediate- or high-risk patients ...

Increasing numbers of patients require aortic valve surgery ... either a homograft or the pretreated stentless xenograft bioprosthesis. Survival of patients after 8 years was about 80% for ...

CALC is the principal failure mode of BHV fabricated from glutaraldehyde pretreated porcine aortic valves or bovine pericardium. Covalent binding of APD to residual glutaraldehyde in pericardial ...