fumigatus, azole-resistance represents a clinically ... the same problem may affect other antifungals with novel mechanisms of action that are in development. For example, the medical antifungal ...

fumigatus has important implications for the scope of clinical antifungal stewardship. Given the human health consequences of disease caused by azole-resistant Aspergillus, it is hardly surprising ...

An example of this is an antifungal drug class called the azoles. There is strong evidence to suggest that azole resistance .

Second, there is a greater chance of drug interactions. Azole antifungals (e.g., fluconazole, itraconazole and voriconazole) alter metabolism of cyclophosphamide, a cytotoxic agent, through ...

The findings, reported in Nature Communications, also solve a decades-long scientific puzzle that’s prevented drugmakers from successfully using azole antifungal drugs to treat visceral ...

Scientists have discovered that the most widely-used class of antifungals in the world causes ... weapons against fungal plant diseases are azole fungicides. These chemical products account ...

While occurrence and risks of azole antifungals in wastewater and meat industry have been studied, their presence in surface water and potential threats to water quality are underexplored. This ...

EU agencies unite to tackle azole fungicide resistance in Aspergillus fungi: Amsterdam, The Netherlands Monday, February 3, 2025, 17:00 Hrs [IST] For the first time, t ...

The mechanism of action of citalopram HBr as ... potent inhibitors of CYP2C19 or CYP3A4 (eg, azole antifungals). May be antagonized by carbamazepine. Increases metoprolol levels.