Mechanisms of antifungal drug resistance involve alterations in the sequence ... For instance, in C. albicans, azole resistance was associated with the presence of an isochromosome (5L) which resulted ...

33 The results of the present study indicate that TTO and terpinen-4-ol have antifungal activity against Candida strains. The mechanism of action of TTO ... alternifolia Cheel (tea tree) oil against ...

fumigatus has important implications for the scope of clinical antifungal stewardship. Given the human health consequences of disease caused by azole-resistant Aspergillus, it is hardly surprising ...

Potent inhibitors of both CYP3A4 and P-gp include azole antifungals (e.g., ketoconazole, itraconazole, voriconazole and posaconazole) and protease inhibitors (e.g., atanazavir). INR: International ...

Human fungal pathogens exemplify a severe threat to health due to their complex infection strategies and the host's immune system's failure to eradicate ...

EU agencies unite to tackle azole fungicide resistance in Aspergillus fungi: Amsterdam, The Netherlands Monday, February 3, 2025, 17:00 Hrs [IST] For the first time, t ...

Azole Therapy: A class of antifungal medications used to treat fungal infections, including those caused by invasive fungi. This Nature Research Intelligence Topic summary is one of 30,000 created ...

"These findings illuminate a critical mechanism that connects local synaptic activity to the broader gene expression changes necessary for learning and memory," said Mark Dell'Acqua, professor of ...

The international team describes their results and the underlying molecular mechanism in Cell Metabolism. Ergothioneine is a natural compound found in certain fungi such as oyster or shiitake ...