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In the first comprehensive, cell-by-cell analysis of brain tissue from individuals with Tourette syndrome, researchers have ...

Dr. Vaccarino concludes: "Our first paper on basal ganglia interneurons of Tourette syndrome was published in 2005, exactly 20 years ago. While there is still much to be learned about the ...

S, Principal Investigator at A*STAR SRL are co-authors of the study. While the current study focuses on basal cell carcinoma (BCC), researchers believe the technology could also be adapted to ...

As the birds gradually mastered their tunes, the team also measured the level of dopamine released in the birds' basal ganglia, a part of the brain involved in learning new motor skills.

Future studies are needed to confirm our findings in additional patients and to elucidate the underlying molecular mechanisms. Our data further suggest exploration of the therapeutic potential of ...

To this end, we combined a dynamic model of dopamine with a neurocomputational model of the basal ganglia with multiple action channels. We also included a dynamic model of tonic and phasic dopamine ...

The basal ganglia have been implicated in action selection and timing ... neurons in the ventrolateral striatum in head-fixed mice on a fixed time reinforcement schedule. Direct pathway stimulation ...

The striatum and the subthalamic nucleus (STN) constitute the input stage of the basal ganglia (BG) network and together innervate BG downstream structures using GABA and glutamate, respectively.