New insights into HIV-1 evolution have come from recent studies on rare individuals who acquired HIV-1 infection despite being homozygous for the CCR5 Δ32 allele, which prevents functional ...

Summary: Maraviroc is the first CCR5 coreceptor antagonist to receive marketing approval from the Food and Drug Administration (FDA) for the treatment of CCR5-tropic human immunodeficiency virus ...

†SNP rs number identity in the NCBI SNP database [143]. The SNP name in parentheses shown in the 'Polymorphism' column is as reported in the 'Association, yes/no' column. ‡MAF reported in the ...