Summary: Maraviroc is the first CCR5 coreceptor antagonist to receive marketing approval from the Food and Drug Administration (FDA) for the treatment of CCR5-tropic human immunodeficiency virus ...

These sites bind to coreceptor CCR5 or CXCR4 on the membrane of the host cell (center panel), an event that initiates steps that culminate in the fusion of the HIV envelope with the host cell ...

Blocking G i protein–coupled receptor signaling by pertussis toxin as well as deficiencies in Gα i2, chemokine receptor 2 (CCR2), CCR5, chemokine ligand 2 (CCL2, also known as monocyte ...

In order to develop a system for detecting low-presence allele variants of the CCR5 gene using digital droplet PCR, we set up a series of experiments on serial dilution of the MT4-14 cells carrying ...

The QTL-allele system underlying two spectral reflectance physiological traits, NDVI (normalized difference vegetation index) and CHL (chlorophyll index), related to plant growth and yield was studied ...

The cytokine CCL5 is elevated following Her2 downregulation and remains high in residual tumors. CCL5 promotes tumor recurrence by recruiting CCR5-expressing macrophages, which may contribute to ...