We observed only one published study in the Sudanese population done to identify the CCR5-delta 32 allele in patients with sickle cell anemia, in which the obtained result was none [12], thus the ...

Using this set of primers, the wild-type CCR5 allele gives rise to a PCR product of 180 bp, whereas the deleted allele is 148 bp. Genomic DNA (50-100 ng) from each individual was amplified in a total ...

To the Editor, The coronavirus disease (COVID-19), which has created the recent pandemic, caused by Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread over to 227 countries ...

The bit of genetic code that causes the gray squirrel species to turn black, they showed, is an allele, or a variant form of a specific gene, called MC1R∆24. But that allele doesn't seem to come ...

In 1996, researchers discovered that CCR5 encodes a receptor on CD4+ cells that HIV uses to enter the cells early on during an infection. People who have two copies of the so-called Δ32 allele don’t ...

The CCR5 ∆32 mutation has shown great promise for creating ... “I think that one has to be very careful about taking out an allele that’s prevalent in one population and moving into ...

Those “multiple fronts” included a poor understanding of how the absence of the CCR5 gene might affect Asian individuals, particularly the way in which the introduced allele, or mutated gene ...

Nature is complicated, viruses are tricky, assumptions are dangerous — and He Jiankui's CRISPR experiment on human embryos was, amazingly, even worse than I first thought.

Adding to his sins, He knew after the gene editing — but before the embryos were transferred to their mother’s uterus — that one of the twins, whom he called Lulu, had a normal CCR5 allele ...

CCR5 is the most commonly used receptor by HIV-1. People who have two mutated copies of the CCR5 allele are resistant to the HIV-1 virus strain that uses this receptor, as the virus cannot enter ...

In addition to chemotherapy, he underwent a haematopoietic stem cell transplant from a donor with two copies of the CCR5 Δ32 allele in 2016. CCR5 is the most commonly used receptor by HIV-1.